It is a relatively uncommon form of epilepsy that constitutes approximately 9-13 of cases. They may also characterize some frontal or temporal nocturnal seizures of sleep-related hypermotor epilepsy, or be considered. The seizures are most typically characterized by complex motor behaviors. Rhythmic movements during sleep may occur in the context of physiological sleep-related motor activity or be part of sleep-related movement disorders such as bruxism, periodic limb movement disorder, restless legs syndrome, and sleep-related rhythmic movement disorder. 2017 Jan 3 88(1):70-77.doi: 10.1212/WNL.0000000000003459. Sleep-related hypermotor epilepsy (SHE), previously known as nocturnal frontal lobe epilepsy, is a form of focal epilepsy characterized by seizures which arise during sleep.

Its outcome is significantly related to disease duration at the time of diagnosis. Sleep-related hypermotor epilepsy: Long-term outcome in a large cohort Neurology. Longer disease duration (>4.5 years) was a significant feature of the patients exhibiting inadequate seizure control.Ĭonclusions: Our data show relatively poor prognosis of SHE on medical therapy. Moreover, it has a relatively poor outcome on pharmacological therapy (16/26, 61.5%). Adolescence age at disease onset (11 years, 6–15), duration less than 1 min, clustering, lack of auras and often uninformative brain imaging (22/25, 88%) are all documented features. It is characterized by being sporadic, with often frontal lobe seizure onset (14/26, 53.8%) and with occasional occurrence in wakefulness. In our series, median age of the patients was 18.5 years. 21 Citations Metrics Opinion statement Sleep has a strong influence on interictal epileptiform discharges and on epileptic seizures. Sleep-Related Hypermotor Epilepsy: Etiology, Electro-Clinical Features, and Therapeutic Strategies Sleep-Related Hypermotor Epilepsy: Etiology, Electro-Clinical Features, and Therapeutic Strategies Nat Sci Sleep. Results: SHE is an uncommon sleep-related focal epilepsy. Ictal semiology and EEGs were reviewed and analyzed by experienced neurologists. Sleep-related hypermotor epilepsy (SHE), previously called nocturnal frontal lobe epilepsy (NFLE), is a focal epilepsy characterized by asymmetric tonic/dystonic posturing and/or complex hyperkinetic seizures occurring mostly during sleep. Patients and methods: This study was carried out on 26 patients with SHE who were subjected to detailed history taking and examination in addition to home video recording, video electroencephalographic (EEG) monitoring and brain imaging. Therefore, the aim of the present study was to identify this disorder among people who were seeking medical advice at Cairo University Epilepsy Unit (CUEU), characterizing its clinical, electroencephalographic and imaging features besides identifying possible indicators of inadequate seizure control on drug-therapy. Some types of epilepsy, such as infantile spasms, tend to cause.

and occur least often shortly after falling asleep. Despite active pharmacological therapy in the management of this disorder, satisfactory seizure control still cannot be achieved. Nighttime seizures occur most often in the early morning around 5 a.m. Objective: Sleep-related hypermotor epilepsy (SHE) is a sleep-related focal epilepsy which is often misdiagnosed.

Sleep related hypermotor epilepsy